locaTE

locaTE is a method for context-specific network inference using local transfer entropy, which uses inferred information about cellular dynamics (RNA velocity, optimal transport, pseudotime, etc.) to estimate directional information transfer between genes.

For a detailed discussion of the method, please see our preprint: Zhang, S.Y. and Stumpf, M.P., 2023. Dynamical information enables inference of gene regulation at single-cell scale. bioRxiv, pp.2023-01.